Issue: 2017 > October > case report

Female urothelial cell carcinoma in a failed kidney graft of a male recipient

H.J.J. de Jongh, E.M. van Duijnhoven, A. Rüland, M.M.A. Abdul Hamid, E.J.M. Speel, K. van de Beek
AbstractFull textPDF


We present a case of a male kidney transplant patient harbouring two kidney grafts of which one is functional. In the failed graft, he developed urothelial cell carcinoma with cells containing XX-chromosome, and female tumour cells were also found in the bladder. The patient underwent donor nephrectomy, was treated with epirubicin bladder instillations, and immunosuppression was tapered. Less than a year before re-transplantation a CT scan showed no abnormalities of the first graft. Transplantectomy before a second kidney transplantation is debated.